Tawanda Gumbo Selected Research

Ethambutol (Myambutol)

1/2022	Rifampin Pharmacokinetics/Pharmacodynamics in the Hollow-Fiber Model of Mycobacterium kansasii Infection.
10/2019	Optimizing ethambutol dosing among HIV/tuberculosis co-infected patients: a population pharmacokinetic modelling and simulation study.
11/2018	Artificial intelligence-derived 3-Way Concentration-dependent Antagonism of Gatifloxacin, Pyrazinamide, and Rifampicin During Treatment of Pulmonary Tuberculosis.
1/2018	Clofazimine for the Treatment of Mycobacterium kansasii.
9/2017	Failure of the azithromycin and ethambutol combination regimen in the hollow-fibre system model of pulmonary Mycobacterium avium infection is due to acquired resistance.
4/2016	Azithromycin Dose To Maximize Efficacy and Suppress Acquired Drug Resistance in Pulmonary Mycobacterium avium Disease.
3/2012	Ethambutol pharmacokinetic variability is linked to body mass in overweight, obese, and extremely obese people.
5/2010	Ethambutol optimal clinical dose and susceptibility breakpoint identification by use of a novel pharmacokinetic-pharmacodynamic model of disseminated intracellular Mycobacterium avium.
4/2010	Efflux-pump-derived multiple drug resistance to ethambutol monotherapy in Mycobacterium tuberculosis and the pharmacokinetics and pharmacodynamics of ethambutol.

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Tawanda Gumbo Research Topics

Disease

66	Tuberculosis (Tuberculoses) 11/2021 - 11/2004
29	Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis) 01/2022 - 08/2005
16	Infections 01/2022 - 11/2004
11	Body Weight (Weight, Body) 01/2022 - 11/2006
9	Pulmonary Tuberculosis 11/2018 - 11/2013
4	Lung Diseases (Lung Disease) 01/2022 - 03/2013
4	Meningeal Tuberculosis (Tuberculous Meningitis) 12/2020 - 05/2010
4	HIV Infections (HIV Infection) 09/2017 - 03/2014
4	Candidiasis (Moniliasis) 12/2015 - 11/2006
4	Overweight 05/2013 - 12/2007
4	Candidemia 05/2013 - 11/2006
3	Extensively Drug-Resistant Tuberculosis 01/2019 - 10/2011
3	Invasive Candidiasis 12/2015 - 12/2007
3	Neutropenia 12/2015 - 03/2007
2	Cough 01/2020 - 01/2017
2	Tuberculous Pericarditis 03/2019 - 11/2015
2	Extrapulmonary Tuberculosis 04/2016 - 03/2014
2	Ototoxicity 12/2015 - 10/2015
2	Aspergillosis 05/2013 - 02/2008
1	Peripheral Nervous System Diseases (PNS Diseases) 04/2021
1	Psychotic Disorders (Schizoaffective Disorder) 04/2021
1	Hearing Loss (Hearing Impairment) 01/2020
1	Chemical and Drug Induced Liver Injury 01/2020
1	Constrictive Pericarditis 03/2019
1	Cystic Fibrosis (Mucoviscidosis) 09/2017
1	Shock 09/2017
1	Malnutrition (Nutritional Deficiencies) 11/2016
1	Nontuberculous Mycobacterium Infections 10/2016

Drug/Important Bio-Agent (IBA)

40	Pharmaceutical PreparationsIBA 11/2021 - 08/2005
16	Isoniazid (Ftivazide)FDA LinkGeneric 01/2022 - 01/2007
12	Rifampin (Rifampicin)FDA LinkGeneric 01/2022 - 11/2007
11	Moxifloxacin (Avelox)FDA Link 11/2018 - 11/2004
11	Pyrazinamide FDA LinkGeneric 11/2018 - 08/2009
9	Ethambutol (Myambutol)FDA LinkGeneric 01/2022 - 04/2010
9	Anti-Bacterial Agents (Antibiotics)IBA 01/2021 - 01/2007
8	Linezolid (Zyvox)FDA Link 11/2018 - 11/2016
5	Amikacin (A.M.K)FDA LinkGeneric 10/2016 - 10/2015
4	Micafungin (FK463)FDA Link 12/2015 - 03/2007
4	EchinocandinsIBA 05/2013 - 10/2007
3	Cycloserine (Seromycin)FDA Link 04/2021 - 11/2018
3	Drug CombinationsIBA 03/2021 - 01/2018
3	avibactamIBA 01/2021 - 01/2018
3	AminoglycosidesIBA 10/2016 - 10/2015
3	Proteins (Proteins, Gene)FDA Link 11/2015 - 01/2002
3	Caspofungin (Cancidas)FDA Link 05/2013 - 12/2005
3	Anidulafungin FDA Link 02/2008 - 11/2006
2	terizidoneIBA 04/2021 - 10/2020
2	Ethionamide (Trecator-SC)FDA Link 01/2021 - 11/2018
2	Biomarkers (Surrogate Marker)IBA 01/2021 - 11/2016
2	ceftazidime drug combination avibactamIBA 12/2020 - 01/2017
2	thiamine triphosphorate (TTP)IBA 01/2020 - 11/2015
2	AerosolsIBA 01/2020 - 01/2017
2	Tigecycline (Tygacil)FDA Link 01/2019 - 01/2016
2	Gatifloxacin (Zymar)FDA Link 11/2018 - 11/2018
2	tedizolidIBA 11/2018 - 11/2018
2	Azithromycin (Zithromax)FDA LinkGeneric 09/2017 - 04/2016
2	Thioridazine (Mellaril)FDA LinkGeneric 09/2017 - 12/2013
2	fropenem (faropenem)IBA 11/2016 - 11/2016
2	Biological ProductsIBA 07/2013 - 12/2005
2	Fluconazole (Zonal)FDA LinkGeneric 02/2008 - 11/2006
1	Pyridoxine (Pyridoxin)FDA LinkGeneric 04/2021
1	Vancomycin FDA LinkGeneric 01/2021
1	Cefazolin (Ancef)FDA LinkGeneric 01/2021
1	RifamycinsIBA 01/2021
1	LactamsIBA 01/2021
1	FluoroquinolonesIBA 01/2021
1	OPC-67683IBA 12/2020
1	1-phenyl-3,3-dimethyltriazene (PDT)IBA 12/2020
1	Ceftriaxone (Ceftriaxon)FDA LinkGeneric 12/2020
1	Nalidixic Acid FDA Link 01/2020
1	Tuberculosis VaccinesIBA 01/2020
1	Indicators and Reagents (Reagents)IBA 01/2020
1	VaccinesIBA 01/2020
1	Kanamycin FDA Link 01/2020
1	Tuberculin (PPD)IBA 01/2020
1	Polymyxin B (Aerosporin)FDA LinkGeneric 01/2020
1	Prednisolone (Predate)FDA LinkGeneric 03/2019
1	tributyl phosphate (TBP)IBA 03/2019
1	RNA (Ribonucleic Acid)IBA 01/2019
1	Antitubercular AgentsIBA 01/2019
1	Minocycline (Cyclops)FDA LinkGeneric 01/2019
1	Levofloxacin (Levaquin)FDA Link 11/2018
1	Penicillin G (Benzylpenicillin)FDA LinkGeneric 01/2018
1	Penicillins (Penicillin)FDA Link 01/2018
1	Capreomycin (Capastat)FDA Link 01/2017
1	Carbapenems (Carbapenem Antibiotics)IBA 01/2017
1	6-chloropenicillanic acid S-sulfoxideIBA 01/2017
1	Aminosalicylic Acid (Rezipas)FDA Link 01/2017
1	Clavulanic Acid (Potassium Clavulanate)FDA LinkGeneric 01/2017
1	Ertapenem (Invanz)FDA Link 01/2017
1	Clarithromycin (Biaxin)FDA LinkGeneric 10/2016
1	Cefoxitin (Cefoxitin Sodium)FDA LinkGeneric 10/2016
1	MacrolidesIBA 04/2016

Therapy/Procedure

28	Therapeutics 03/2021 - 11/2006
7	Duration of Therapy 01/2022 - 12/2009
4	Drug Therapy (Chemotherapy) 11/2018 - 01/2007
2	Aftercare (After-Treatment) 10/2020 - 11/2006
1	Intravenous Infusions 01/2018
1	Injections 01/2018
1	Salvage Therapy 01/2017